Novel method for performing carbonic anhydrase histochemistry and immunocytochemistry on cryosections.
نویسندگان
چکیده
منابع مشابه
Carbonic anhydrase II deficiency a novel mutation.
Carbonic anhydrase II (CA II) deficiency is an extremely rare autosomal recessive disorder, characterised by a triad of osteopetrosis, renal tubular acidosis and cerebral calcifications. A 12 year old boy with classical features of CA II deficiency is reported who was found to be homozygous for the mutation in CA II gene and parents were heterozygous for the same mutation .To the best of our kn...
متن کاملInvestigation of solvent effect on the active site energy of Carbonic Anhydrase and Ribonucleotide Reductase
Enzymes catalyze many biological reactions. The rates of chemical reaction in the presence ofenzymes are, in some cases, accelerated more than 10 orders of magnitude relative to thecorresponding rates in solution.In this paper a comparison between optimized structures of two enzyme molecules in aspect ofenergy and dipole moment in different conditions including presence of metallic ion, without...
متن کاملSynthesis and carbonic anhydrase inhibitory properties of novel uracil derivatives.
Carbonic anhydrase (CA) inhibitors are valuable molecules based on several therapeutic applications, including antiglaucoma activity. In the present study, inhibition of two human cytosolic carbonic anhydrase isozymes I and II with some uracil derivatives (3-9) were investigated. Compounds 3-9 showed KI values in the range of 10.83-464 μM for hCA I and of 28.88-778.5 μM against hCA II, respecti...
متن کاملCarbonic anhydrase under pressure
Investigations of the rapid enzyme carbonic anhydrase have now been extended by crystallographic analysis at high CO2 pressures to examine the movements of water molecules in different steps of the catalysis. The rate of catalysis seems well explained by the assembled observations.
متن کاملGastric Carbonic Anhydrase In
Davenport and Fisher (1938) reported the discovery DOGS P School of Medicine of large amounts of carbonic anhydrase in the gastric mucosa of cats, rats and rabbits. Davenport (1939) demonstrated that carbonic anhydrase is present in high concentration in the parietal cells and in lower concentration in the cells of the surface epithelium of the gastric mucosa of cats and rats. When those invest...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Histochemistry & Cytochemistry
سال: 1992
ISSN: 0022-1554,1551-5044
DOI: 10.1177/40.8.1377737